True Phenotyping and Genotyping on One Report from One Sample

The addition of phenotypic to genotypic testing, as found in PhenoSense GT®Plus Integrase, is noted in US Department of Health and Human Services (DHHS) guidelines as generally preferred for patients who may benefit from drug resistance testing due to known or suspected complex drug resistance patterns.1 Monogram offers two assays that combine phenotypic and genotypic drug susceptibility data into one report:

  PhonoSense GT PhenoSense GT plus Integrase
Drug classes tested NRTIs, NNRTIs, PIs NRTIs, NNRTIs, PIs, and INIs
Monogram test code V7000 M7000
LabCorp test number  551690 551920

Combined Testing Process

These comprehensive tests allow advanced, practical insight into the resistance continuum and overcome limitations associated with either genotyping or phenotyping alone. Even in complex cases, PhenoSense® GT and PhenoSense GT Plus Integrase perform the genotype and phenotype from a single blood sample so that it is possible to resolve disagreement between them.

PSGT Process

References

Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV. Department of Health and Human Services. Available at https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/AdultandAdolescentGL.pdf. Accessed April 30, 2021.