The HCV NS5B Drug Resistance Assay is a genotypic (sequencing) resistance assay that analyzes the nonstructural (NS) 5B region of hepatitis C virus (HCV) genotypes 1a or 1b using next-generation sequencing (NGS) techniques. Amino acid substitutions in the NS5B region are identified, and a viral susceptibility call for the direct-acting agents (DAAs) that inhibit the HCV RNA polymerase is reported as either “resistance possible” or “none/undetermined”.
|Test Name||Labcorp Test Number||Limitation||Specimen Collection||Turnaround Time|
|Hepatitis C Virus (HCV) NS5B Drug Resistance Assay||550505||For patients with HCV genotype (subtype) 1a or 1b and a viral load ≥ 1000 IU/mL||
2 mL plasma, EDTA or PPT tube, shipped frozen
10 to 14 days