GenoSure PRIme

GenoSure PRIme®

GenoSure PRIme® is the first HIV resistance test to provide genotypic resistance information for all Department of Health and Human Services (DHHS)-preferred first-line options, including integrase inhibitors.

Comprehensive Profile in Single Test

GenoSure PRIme is a comprehensive resistance test for four classes of HIV drugs, including protease inhibitors (PIs), nucleoside reverse transcriptase inhibitors (NRTIs), nonnucleoside reverse transcriptase inhibitors (NNRTIs), and integrase inhibitors (INIs).

Consider GenoSure PRIme for baseline HIV resistance and detection of transmitted resistance at initiation of therapy.1

 

To Aid in Therapy Decisions for Treatment-experienced Patients

Consider a genotype test like GenoSure PRIme when contemplating changes to your patient’s treatment regimen after first or second line failure as stated in the DHHS guidelines1


Features of GenoSure PRIme
 

  • Evaluates the HIV-1 polymerase (pol) region, including the complete protease and integrase coding regions and amino acids 1-400 of reverse transcriptase.
  • Provides an assessment of drug susceptibility: sensitive, resistance possible, or resistant.
  • Appropriate for the evaluation of patient specimens with HIV-1 viral loads of >500 copies/mL.
  • Uses Monogram’s proprietary HIV-1 genotype algorithm, which is based on a database of more than 100,000 matched HIV-1 genotype-phenotype results.

For more information, contact Monogram client services at 800-777-0177.

*If the assay fails on the initial attempt, HIV-1 RNA quantitation will be performed. If the result is <500 copies/mL, the viral load will be reported and the client will be billed.

References

  1. Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV. Department of Health and Human Services. Available at https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/AdultandAdolescentGL.pdf. Accessed April 30, 2021.