PhenoSense GT® Plus Integrase is the first commercial assay to provide comprehensive genotypic and phenotypic drug resistance information for four classes of antiretroviral drugs, including nucleoside/nucleotide, non-nucleoside, protease, and integrase inhibitors, in a single report. The addition of phenotypic to genotypic testing, as found in PhenoSense GT Plus Integrase, is noted in US Department of Health and Human Services (DHHS) guidelines as generally preferred for patients who may benefit from drug resistance testing due to known or suspected complex drug resistance patterns.1
PhenoSense GT Plus Integrase is also available as a reflex from a viral load test if the viral load result is ≥500 copies/mL. The LabCorp test numbers are 550711 (graphical viral load with reflex to PhenoSense GT Plus Integrase) or 550625 (nongraphical viral load with reflex to PhenoSense GT Plus Integrase). Reflex orders through Monogram do not have unique reflex order codes. Please note: PhenoSense GT Plus Integrase is not indicated when the HIV-1 viral load is <500 copies/mL plasma.*
*If the assay fails on the initial attempt, HIV-1 RNA quantitation will be performed. If the result is <500 copies/mL, the viral load will be reported and the client will be billed.